One man has died and six others are injured following three separate violent incidents in Melbourne’s CBD.

Two men were found in a critical condition with stab wounds on Bourke Street just before 6am on Sunday and taken to hospital.

One of the men, who has not been formally identified, later died.

No arrests have been made and Bourke Street has been shut between Elizabeth Street and Queens Street while homicide squad detectives investigate what happened.

Earlier, two men were injured in what police have described as a “large affray” outside Inflation nightclub on King Street.

An unidentified man was critically injured and a 19-year-old man suffered suspected serious injuries.

Meanwhile, the hunt is on for two men wanted over an attack in Southbank.

It’s believed two men set upon a group as they left a bar at Riverside Quay at around 12.40am.

A 25-year-old Springvale man was struck and fell, hitting his head on the ground.

Two other men suffered facial injuries. 

Police say the men who appeared to be the aggressors fled the scene.

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